Intrauterine insemination or IUI is the initial step in managing male factor infertility.

The procedure involves the placement of about 0.3 ml – 0.5 ml of washed, processed and concentrated sperm in to the uterine cavity by means of a transcervical catheter.

Washing will remove the seminal factors and isolate pure sperm. if unwashed semen containing the seminal plasma is introduced in the uterine cavity it may result in severe cramping due to prostaglandins.

The success rates range from 8% - 20%