Preimplantation Genetic Diagnosis (PGD) was developed in the late 1980s as an alternative to prenatal diagnosis and possible termination of pregnancy of an affected fetus for couples who are at risk of passing on serious genetic diseases to their children.

Preimplantation Genetic Diagnosis technique requires to test embryos for genetic disorders before it implants in the womb (uterus). It avoids the need for the termination of pregnancy.

An increasing number of genetic disorders can now be diagnosed by this technique.

It should be noted that genetic disorders could be due to either a single gene disorder or more than one gene.

In cases of recurrent chromosomal abnormalities such as Down’s syndrome and recurrent miscarriages caused by parental translocations, the number, and character of several chromosomes can be determined.